Critical Immune Defense

Sale price$65.00 USD
Size: 1 Bottle

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Critical Immune Defense is a powder that you sprinkle just a small amount on your dog or cat's food. It TASTES GREAT - even for the most finicky of pets.

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    Made In The USA To The Highest Quality Standards

    VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

    Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.

    Your pet's immune system is the key to its health! Here's why:

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

    Let’s face it. Your pet lives in a world filled with contamination.

    They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

    The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

    Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

    What do you do?

    You need to put your pet’s immune system in overdrive!

    Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

    The doctors agree

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”

    Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    Pet owners CAN make a difference.

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    – Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    More cats and dogs are being diagnosed with cancer than ever before. 

    “Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Frequently Asked Questions

    Verified Product Reviews

    average rating 4.7 out of 5
    Based on 1481 reviews
    • 5 Stars
      1227 Reviews
    • 4 Stars
      149 Reviews
    • 3 Stars
      72 Reviews
    • 2 Stars
      9 Reviews
    • 1 Star
      24 Reviews
    93% of reviewers would recommend this product to a friend
    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Customer photos and videos
    1481 Reviews
    Reviewed by Debbie M.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Soft-Coated Wheaten Terrier
    Cat Breed
    Siberian
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Great for cats & dogs!

    Our Siberian cat died of a cancerous tumor last year. So I did research and found this product for our other cat and dog. I don't want either of them to get cancer. My husband & I love a mushroom supplement so giving them the pet version seemed right. I sprinkle it on their food every meal. They love it. The vet says both pets are extremely healthy. Both are over 10 yrs old.

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Debbie, thank you for sharing your story—your pets are absolutely beautiful, and we’re so sorry for your loss of your sweet Siberian cat 💛. It’s clear how deeply you care, and we’re thrilled to hear that both your senior cat and dog are thriving with Critical Immune Defense in their routine. Sprinkling it on each meal is such a great way to support their health, and we love that your vet sees the difference too.🐾

    Reviewed by Steven B.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Pitbull Terrier
    Pet Problem(s)
    • Tumor
    • Low Energy
    • Joint Pain
    • Inflammation
    Will Consume Product
    Enjoyed
    Pet Happiness
    Tail Wagging

    HAS HELPED IMMENSELY!

    About 2 months ago we found several lumps on our 11yo girl Diem. We lost our 9yo boy Bennett back in October and it was devastating. If only I had come across this back while he was still alive I feel like it could’ve made a considerable difference. Since she’s been on the critical immune defense no more lumps have formed and the ones she has have either not increased in size! Her energy levels have increased too. It has been such a relief to my wife and I knowing we will have more time with her. I would highly recommend this to anyone wanting to boost their pets immune system!

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    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Steven, thank you for sharing, and we're so sorry about Bennett. 💛 We’re thrilled to hear Diem is doing better—more energy and no new lumps is amazing news! 🐾 She looks so strong and loved. Wishing you many more happy moments together!

    Reviewed by Laurie S.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Rhodesian Ridgeback
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Dogs love it!

    The dogs love it, I add it to their food with a little warm water. I don't worry as much about their health knowing that I'm providing this great supplement for them

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Laurie, thanks so much for sharing! Your pups look so happy and healthy—what a joy to see! 🐶❤️ It’s wonderful to hear they love the supplement mixed with a little warm water, and even better that it gives you peace of mind about their health. You’re clearly doing an amazing job keeping them well cared for!

    Reviewed by Patricia R.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Mixed Breed
    Pet Problem(s)
    • Tumor

    Helped My Cat

    I decided to try this after reading several reviews. I give it to my Bulldog/Boxer mix, Wilson, as a preventative. My Calico cat, Cali, developed a quarter-sized lump that she’d licked raw on the surface, so I decided to start giving it to her. Her lump is no longer raw/sore and has shrinked in size. She has stopped licking it. I am still going to take her to the vet to have it removed, but I definitely saw a drastic improvement. Thank you for making something that I can give to both my cats and dog. I definitely recommend this product.

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    Pet Wellness Direct

    Thank you for sharing, and what a beautiful duo Wilson and Cali are! 🐾 We're so glad to hear that Critical Immune Defense is helping both your Bulldog/Boxer mix and sweet Cali. It's amazing that her lump is no longer raw and has shrunk—what a relief! 😻 We love that you're using it preventatively too. Wishing you a smooth vet visit and continued good health for both your furry companions!

    Reviewed by Fabian N.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Pitbull Terrier
    Pet Problem(s)
    • Cancer
    Will Consume Product
    Enjoyed
    Pet Happiness
    Tail Wagging

    Wonderful product

    She was diagnosed with mammary cancer. She had during January. The tumors returned with swelling. The swelling has decreased dramatically and her energy is so much better. Great product!!!

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    Pet Wellness Direct

    Hi Fabian, thank you for sharing—your girl looks so strong and beautiful! 💕 We’re so glad to hear her swelling has gone down and her energy is up. Wishing her continued healing and happy days ahead! 🐾