Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.
Turkey Tail Mushroom
This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.
Reishi Mushroom
This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.
Shiitake Mushroom
According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.
Maitake Mushroom
Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.
White Turmeric Root Extract
Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
liver damage.
Ingredients & Usage Direction:
(Approximately 70 Scoops Per Container)
(Approximately 70 Scoops Per Container)
VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.
Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.
Let’s face it. Your pet lives in a world filled with contamination.
They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.
The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.
Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.
You need to put your pet’s immune system in overdrive!
Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.
“As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”
- Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.
“It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”
– Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.
“Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.
“Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”
- Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.
VetSmart Formulas were originally designed for veterinarians. This means they deliver the clinical-strength quality and efficacy veterinarians demand in products they provide and recommend. They are wheat-free and contain no artificial colors or flavors. Moreover, it can be used along with most products and prescription medications available for pet consumption.
Thousands of dogs in all sizes and weights continue to benefit
every month from VetSmart Formulas to boost their immune system and
overall health.
If your dog has a situation similar to the other dogs you may have read
about in our reviews, then this product may likely help your dog too.
Critical Immune defense helps protect your pet against:
Abnormal cell growth
Harmful pathogens such as bacteria, viruses, fungi, and parasites
Inflammation
Infection
Cardiovascular disease
Hormone imbalance
High blood pressure
Arthritis
Liver damage
… and more.
That being said, every dog is unique and
unfortunately there are some dogs that have problems this formula cannot
solve. This is exactly why we offer a 30 day risk-free money back
guarantee.
Great news... not only do we offer a 30-day money back guarantee, we also provide Free Shipping on Domestic Orders Over $100.
If you’re trying this product for the first time and only want
to start with 1 bottle, we only charge you our cost of $5.95 for postage and handling. (US Domestic)
When your pet’s immune system is functioning at an optimal
level, it will naturally balance the “normal activity” that should take
place. The immune system fights infections, and removes harmful viruses
and bacteria, and it slows the aging process. A strong immune system
will also boost Natural Killer (NK) and T-Helper cell production that
helps prevent and slow cancer cell reproduction. So, a strong and
healthy immune system will keep your pet safe and healthy!
The time to start any preventative action is before your pet
has an issue. As dogs and cats age, their immune systems are not as
strong, and they are more susceptible to diseases. A weak immune system
in dogs and cats can cause a variety of diseases such as infections,
diabetes, osteoarthritis and cancers. Be a proactive pet owner and start
boosting your pet’s immune system while they are younger and BEFORE
they have an issue.
Not likely. However, if you know (or think) that your pet has a
sensitive stomach ease into the product slowly. Start with 1/3 or 1/2
the recommended dose and work your way up to full dose over a 1-2 week
period. If you notice any issues, simply stop using the product or cut
back to find the level that works for your pet.
Yes, absolutely! There is no problem using all the products together. And… good for you for being on top of your pet’s health!
Yes. Our product is all-natural and designed to be taken with
chemotherapy medications. It will help boost their immune system that
might be compromised by the chemotherapy medications. If your pet is
being treated for any serious medical condition, we always suggest that
you discuss the use of any supplements with your veterinarian. You can
simply bring the bottle to them during a visit or take a photo of the
label and share it with your vet.
Yes. Our product is all-natural and designed to be taken with
prescription medications. It will help boost their immune system that
might be compromised by the medications. Again, we always suggest that
you discuss the use of any supplements with your veterinarian. You can
simply bring the bottle to them during a visit or take a photo of the
label and share it with your vet.
No pet is too old to start using an all-natural product that will help
them live a better and longer life! It’s similar to someone who starts
exercising at 80 years old. Every bit helps! Start now and you will help
to prolong your pet’s lifespan!
We can’t guarantee that, but what we do know is our product is very
effective at boosting your pet’s immune system which helps fight all
types of diseases such as cancers. The research on the ingredients in
Critical Immune Defense is very extensive and Asian cultures have used
these ingredients effectively for many centuries.
Critical Immune Defense is very easy to give to your pet. It’s a powder
that you simply sprinkle on their food. It has a natural hypo-allergenic
chicken flavor that appeals to both dogs and cats, and most pets love
the flavor. We offer a 30-day money back guarantee if they don’t like
the taste.
We agree. The numbers are frighteningly high! These statistics were
published by the Veterinary Cancer Society. There is so much research
and so many clinical studies on the percentages of dogs and cats that
get cancer. You can Google it and see the various studies online.
No, they are not. Turkey Tail Mushroom, also known as Coriolus
Versicolor, is a common type of mushroom that has the shape and color of
a turkey tail. What is unique about the Turkey Tail Mushrooms that we
use in Critical Immune Defense is the mushrooms are harvested at a very
young age when the polysaccharide K (PSK) and peptides are the most
concentrated, and these active compounds boost the immune system. As a
reference, polysaccharide K (PSK) is an approved mushroom product to
treat cancer in Japan.
Here’s a way to think about it. High blood pressure is known as the
“silent killer.” That’s because people may have high blood pressure for
many years and not notice it. However, because there are no visible
signs does not mean nothing is happening in your body. The same is the
case with boosting your pet’s immune system. You may notice that your
pet is more lively or peppy, or you may not notice anything at all. Keep
in mind that not seeing a visible result does not mean the product is
not working.
We love this question! Our product is one of the most powerful immune
boosters for pets on the market. We have combined a blend of four
mushrooms along with turmeric and vitamins to create what we feel is the
absolute best immune booster for pets. Our ingredients are standardized
to the highest potency and the product is veterinarian strength. We
invite you to compare the labels and the ingredients in our product to
any others on the market to see for yourself!
Call your vet immediately and explain the situation. If your vet is not available, contact the ASPCA Animal Poison Control Center at
888-426-4435.
Most mushrooms are very beneficial to humans and both cats and dogs,
and less than 1% of mushrooms are harmful. The mushrooms that we use in
Critical Immune Defense are “medicinal mushrooms” and they have been
used to boost immune systems for centuries and are proven to be safe and
effective for cats and dogs. For more than 30 years medicinal mushrooms
have been approved as cancer treatments in Japan and China. More
recently, the U.S. Food and Drug Administration (FDA) has approved
clinical trials for Turkey Tail and other medicinal mushrooms.
We didn't discover turkey tail," says lead investigator
Leanna J. Standish, PhD, ND, LAc, FABNO, Medical Director of the Bastyr
Integrative Oncology Research Center. "It's been used in Asia for
thousands and thousands of years, and it turns out to be a really potent
immune therapy. The significance, I think, is that we're bringing a new
medicine to cancer patients in the U.S."
Studies are being conducted at several U.S. research
universities, including the University of Pennsylvania School of
Veterinary Medicine to gather data on the cancer and tumor-fighting
effects of mushrooms in dogs, and the development of transformative
cancer therapy for pets.
Please do your own online research to learn more about the
benefits of the mushrooms in our product and the research being
conducted. It is quite amazing!
Verified Product Reviews
This product is rated 4.7 of 5.0 stars.
It has received 1550 reviews.
I think it is helping!
Thanks for sharing, Virginia! Your Cavaliers look absolutely precious 🐶❤️. We’re so glad you’re seeing signs of improvement—every little bit counts, and we’re cheering on their continued progress! 🐾
I have been using this as recommended every day for about 6 months for my five year old pup, Dudley. He has very serious allergies and I hoped that this would help give him some relief. He remains on medication and also has immunotherapy injections but continues to have symptoms. I am determined to ensure that he has the best life possible. I plan to keep giving it to him.
Thank you for sharing Patricia, Dudley looks like such a sweet and strong pup 💛🐾. We know how tough allergies can be, and it’s clear you’re doing everything to give him the best life. Even if progress feels slow, your dedication means the world—and we’re hopeful Critical Immune Defense will keep supporting him alongside his other treatments!
Miss Reeza wouldn’t start her day without her Critical Immune Defense!! Her mom makes sure she has plenty on hand!!! 💯♥️👍
Hi Mary, Miss Reeza looks absolutely adorable in her photo—her bright eyes and happy smile say it all 🐶❤️. We’re thrilled to hear she won’t start her day without her Critical Immune Defense—what a routine! Your dedication to keeping her stocked and supported shows just how much you care. Here’s to Reeza staying healthy, strong, and full of joy every single day! 💯🐾
My goldendoodle Cooper was diagnosed with anal gland cancer at 61/2 years old. He had surgery followed by 6 rounds of chemotherapy. When we stopped chemo , our vet has treated him with a steroid injection for about a year now. All of a sudden we saw Coopers health decline again. Vet took blood and chest X-ray and his cancer has spread. I started coopers on pet Defense about a month ago and I can see he feels better. We also started to feed him boiled chicken and vegetables once a day keeping carbs low. I don’t know how long Cooper will be with me but I want to make sure I am doing everything I can to keep him healthy and Pet Defense is working in front of my eyes.
Hi Donna, thank you for sharing Cooper’s journey. He looks so strong and sweet in his photo 💛🐾. We’re glad to hear that Critical Immune Defense is helping him feel better—your care, from chemo to a low-carb diet, is truly inspiring. Cooper is lucky to have you by his side, and we’re honored to be part of his journey.
Just started two weeks ago in en effort to reduce and/or eliminate lipomas. So far my dog tolerates it but doesn’t love it. My only complaint is based on the dog’s size and recommended treatment amount are not made clear in the product website. As a result, you start to runout before the month is up and the next bottle is received.
Hi Barry, thank you for the honest and thoughtful feedback. Your pup looks wonderful in the photo—such a sweet face and strong spirit 🐾💛. We’re glad to hear they’re tolerating the product well so far, especially as you’re working to reduce those lipomas. We completely understand the concern about dosage clarity and timing, and we appreciate you pointing that out—it’s something we’re actively working on improving. Your care and attention to your dog’s health really shines, and we’re hopeful you’ll continue to see positive changes ahead!
