FIGHT VIRUSES, DISEASES, AND CANCERS.

Critical Immune Defense for Dogs & Cats

Sale price$65.00 USD
Size: Small Bottle | 70 Scoops

There simply isn't another product of this quality and strength - with THOUSANDS of testimonials about the results - available on the market!

Critical Immune Defense is a safe, all-natural immune booster that can add years to the life of your dog or cat. Made in the USA.

✔︎ Boosts immune system

✔︎ Reduces inflammation

✔︎ Promotes normal cell growth

✔︎ Protects against toxins in food, water & environment

✔︎ Supports long-term health in both cats and dogs

Critical Immune Defense is a powder that you sprinkle just a small amount on your dog or cat's food. It TASTES GREAT - even for the most finicky of pets.

"Wish there was a human version!! Our large male German shepherd was getting growths on his neck and by his eye. They were getting larger. I saw this product and ordered one canister, not expecting much. However, within 2 weeks, the growths were getting smaller. They finally disappeared! We now give this as a preventative to both of our dogs! Highly recommend it!! Worth the money!!" - Carla

“My cat is 15 and has feline herpes. In the past, I have given her lysine with very little results. Since taking Critical Immune Defense I have seen a steady improvement. Hardly any eye discharge and her nose isn’t wet anymore. No difficulty breathing at all. My son said, “What took you so long to find this stuff?” I also give it to my 3-year-old dog, she’s healthy but …..just in case. They both eat it and have no problem eating all their food.” - Lisa

"This supplement has saved my dog’s life. She is a completely different animal, now. She’s an 11-year-old Maltipoo and was diagnosed with lymphoma last April. She was on chemotherapy, and this supplement along with a healthy greens supplement for 3 months, and her cancer is gone. I have kept her on these supplements, and they continue to work miracles in her little body. She also used to have the worst skin issues, constantly having things removed, and she was just generally not healthy. It’s unbelievable how healthy, happy, and energetic she is. It truly is a miracle!" - Adelle

“I have a rescue and keep 8 senior and special needs cats. I give them this for cats, and it has proven to extend the lives of those who were in danger of losing their lives from cancer, renal failure, and, frankly, only God knows what else! I am grateful for this formula being available for seniors we adore and aren’t really ready to cross the 🌈 yet❣️👍😻 This was Foxy Loxy. He had been failing(14 yrs old), but as he received Pet Wellness Support, he recovered his enjoyment of life, and I could love him for 2 more years❣️ I have other kitties' who had experienced similar recoveries through Pet Wellness. Thank you again!”❣️- Mat

Your pet's immune system is the key to its health! Here's why:

In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

Let’s face it. Your pet lives in a world filled with contamination.

They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

What do you do?

You need to put your pet’s immune system in overdrive!

Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

"The immune system acts like a nonstop housekeeper", describes Dr. Donna Raditic, an American College of Veterinary Nutrition (ACVN) diplomate in Athens, Georgia.

It identifies potentially harmful pathogens like bacteria, viruses, fungi, and parasites, then works to eliminate them before they can do harm.

And a pet's immune system monitors cells to ensure they’re working properly.

“When other cells are aging or functioning abnormally—such as a cancer cell reproducing too rapidly—the immune system attempts to step in and maintain proper physiological function and balance,” Dr. Raditic explains.

Your pet's immune system is the key to its health! Here's why:

In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

Let’s face it. Your pet lives in a world filled with contamination.

They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

What do you do?

You need to put your pet’s immune system in overdrive!

Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

"The immune system acts like a nonstop housekeeper", describes Dr. Donna Raditic, an American College of Veterinary Nutrition (ACVN) diplomate in Athens, Georgia.

It identifies potentially harmful pathogens like bacteria, viruses, fungi, and parasites, then works to eliminate them before they can do harm.

And a pet's immune system monitors cells to ensure they’re working properly.

“When other cells are aging or functioning abnormally—such as a cancer cell reproducing too rapidly—the immune system attempts to step in and maintain proper physiological function and balance,” Dr. Raditic explains.

Key Ingredients

Turkey Tail Mushroom

This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

✔︎ Delivers significant amounts of tumor-fighting Polysaccharopeptides (PSPs)

✔︎ Approved by the United States Food & Drug Administration for use in treating prostate and breast cancer in humans

✔︎ Proven to delay the growth of cancerous tumors in dogs and improve their survival rate

Reishi Mushroom

This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

✔︎ Contains beta-glucans that increase the immune system’s T-cell levels

✔︎ Lowers inflammatory responses caused by stress, poor diet, and other environmental factors

✔︎ Contains ganoderic acids that have been shown to lower cholesterol levels and blood pressure

Shiitake Mushroom

According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

✔︎ Contains all 8 essential amino acids as well as linoleic acid, an essential fatty acid

✔︎ Used in Japan to treat heart disease, hepatitis, high blood pressure, and infectious diseases

Maitake Mushroom

Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

✔︎ Contains beta-1, 6 glucan polysaccharide components that stimulate the immune system and reduce abnormal cell growth

✔︎ Used in Asia to help minimize the toxic effects of radiation and chemotherapy treatment

White Turmeric Root Extract

Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and liver damage.

Our proprietary extract is six times more bioavailable than standard turmeric root, which means it’s more effectively absorbed into your pet’s body and they need less of it to get the same effect. It’s also colorless and milder tasting, making it easier to handle -- and tastier for your pet! No more turmeric stains!

The doctors agree.

Mushrooms = Anticancer Activity

“As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”

Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

Pet owners CAN make a difference.

“It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

– Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

More cats and dogs are being diagnosed with cancer than ever before. 

“Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.

“Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

Your pet’s immune system is one of the most critical parts of its health.

It’s your job to feed and nourish it, and make sure it operates at optimal levels to fight disease and cancers.
Order now

Your pet’s immune system is one of the most critical parts of its health.

It’s your job to feed and nourish it, and make sure it operates at optimal levels to fight disease and cancers.
Order now

Not only is it easy to use (just sprinkle it over your pet’s food) -- your pet will love the taste!

Scoops/Bottle: 70 Small | 210 Large

NEW Enhanced Formula

Discover Our Enhanced Formula!

We've improved our formula! The new product may appear lighter in color and have a slightly different texture (but the same great taste), thanks to our innovative use of the fruiting body and mycelium of the four mushrooms, instead of mushroom extracts.

 Why the Change?

Traditional mushroom extracts are processed using heated water, which is then sprayed to create a powder. Our research suggests that this heat processing can diminish the valuable nutrients in the mushrooms.

Understanding Fruiting Body and Mycelium

Fruiting Body: This is the part of the mushroom you're familiar with—the cap and stem.

Mycelium: These are the nutrient-packed roots and base of the mushroom.

We use the entire mushroom, grinding it into a nutrient-dense powder that boasts higher levels of beta-glucans and polysaccharides than extract powders. Independent testing has shown that our new mushrooms contain up to 250% more beta-glucans and polysaccharides.

Research-Backed Benefits

According to research published by the National Library of Medicine, beta-glucans and polysaccharides are renowned for their metabolic and immunomodulatory properties, including anticancer, antibacterial, and antiviral effects. In some countries, the mushrooms we use in Critical Immune Defense are prescribed not only to prevent cancers and diseases but also to effectively treat them.

Organic and Sustainable

Our mushroom blend is organically grown in Canada on sustainable farms using patented and breakthrough growing processes to enhance the full spectrum of bioactive compounds. It doesn't get any better for your pet!

Experience the powerful benefits of our enhanced formula and give your pets the best in health and wellness!

Made in the USA to the highest quality standards.

VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved pet’s health.

Frequently Asked Questions

average rating 4.8 out of 5
Based on 1413 reviews
  • 5 Stars
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    155 Reviews
  • 3 Stars
    58 Reviews
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    5 Reviews
96% of reviewers would recommend this product to a friend
Effectiveness
Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
Customer photos and videos
1413 Reviews
Reviewed by Terry H.
Verified Buyer
Review posted
I recommend this product
Rated 5 out of 5
Pet Age
10+ Years
Dog Breed
Labrador
Pet Problem(s)
  • Low Energy
  • Inflammation
  • Hip Pain
  • Joint Pain
  • Limp
Will Consume Product
Devoured
Pet Happiness
Tail Wagging

Critical Immune Defense for Dogs & Cats

This is a great product. We have a lab that has lupus an thought we were going to lose him but this product totally turn him around. He's almost 12 yrs old an doing great!

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Pet Wellness Direct

Thank you for sharing — it’s wonderful to hear your almost 12-year-old Lab is doing great after such a scary lupus diagnosis. 🐾 We’re honored Critical Immune Defense could help support his turnaround and continued strength. ❤️

Reviewed by John C.
Verified Buyer
Review posted
I recommend this product
Rated 5 out of 5
Pet Age
3 - 5 Years
Dog Breed
Labrador
Cat Breed
Mixed Breed
Pet Problem(s)
  • Tumor
Will Consume Product
Enjoyed
Pet Happiness
Tail Wagging

Dog is responding better every day.

I bought your product for my 15-year-old yellow lab Colonel Trump. He actually does well for his age, but he was starting to scratch quite a bit and the groomer thinks he has a yeast disease. He also has a few bumps on his neck area and head. Nothing bad. But he doesn’t scratch as much since using your product and I’m excited about that. I also have a 16-year-old cat that is an indoor cat and I have a four year-old dachshund Beamer. What would you suggest they take. Both are an excellent health with no problems.

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Pet Wellness Direct

Thank you for sharing Colonel Trump’s update — it’s wonderful to hear that at 15 years old, your yellow Lab is scratching less and responding better each day. 🐾 For ongoing support, Critical Immune Defense is a great option for senior pets like Colonel and can also be used preventatively for your 16-year-old cat. For your healthy 4-year-old Dachshund Beamer, many pet parents choose it as gentle immune and inflammation support as well. We’re glad all three are doing well and appreciate you taking such great care of them. ❤️

Reviewed by Kristine P.
Verified Buyer
Review posted
I recommend this product
Rated 5 out of 5
Pet Age
10+ Years
Dog Breed
Other
Pet Problem(s)
  • Stress
  • Hip Pain
  • Tumor
Will Consume Product
Enjoyed
Pet Happiness
Just Right

Great help!

Purdy, our 10 yo Anatolian, had two major surgeries this summer, and was slow to recover. With the vet’s approval, we added this, and she’s bounced back to her happy self!

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Pet Wellness Direct

Thank you for sharing Purdy’s wonderful progress, her photo is adorable! 🐾 After two major surgeries, it’s so encouraging to hear that your 10-year-old Anatolian has bounced back and is feeling like her happy self again. We’re glad, with your vet’s approval, this could support her recovery and renewed energy. ❤️

Reviewed by connie k.
Verified Buyer
Review posted
I recommend this product
Rated 5 out of 5
Pet Age
10+ Years
Dog Breed
Pitbull Terrier
Pet Problem(s)
  • Tumor
  • Cancer
Will Consume Product
Devoured
Pet Happiness
Just Right

Diesel

My dog Diesel was diagnosed in October with cancerous tumors in his left lung, I purchased this right after and and we're on our second bottle now. He's doing very well so far, I mix it in with some wet food , he thinks he's getting a treat.

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Pet Wellness Direct

Thank you for sharing Diesel’s update — his photo is great!! 🐾 After his lung tumor diagnosis, it’s encouraging to hear he’s doing well and already on his second bottle. We’re glad he enjoys it mixed with wet food and are wishing him many good days ahead. ❤️

Reviewed by Darlene S.
Verified Buyer
Review posted
I recommend this product
Rated 5 out of 5

Lucy is 13 1/2 years old/acts 1/2 her age...like 7

My Lucy was really slowing down... slept most of the time. She used to love to go for walks, ride in the car, and ride on our golf cart... She got to the point where she couldn't (or didn't want to) jump into the car, or the golf cart, and didn't get excited about going for walks... I literally had to pick her up to go the car or the golf cart. That all changed. After reading all the comments about Critical Immune Defense, I thought why not try it. We noticed a difference almost immediately and within 2 weeks she was like a dog half her age. She jumps into the car, on the golf cart and can't wait to go on a walk. She has a fatty tumor on her chest that has started to shrink. Thank you for this wonderful product.

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Pet Wellness Direct

Thank you for sharing Lucy’s amazing progress — her video is terrific! 🐾 At 13½, it’s incredible to hear she’s gone from slowing down and needing help into the car and golf cart to jumping in on her own and acting like a dog half her age. And with her fatty chest tumor starting to shrink, that’s even more encouraging. We’re so glad Critical Immune Defense is helping her feel joyful and active again. ❤️

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