Critical Immune Defense

Sale price$65.00 USD
Size: 1 Bottle

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Critical Immune Defense is a powder that you sprinkle just a small amount on your dog or cat's food. It TASTES GREAT - even for the most finicky of pets.

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    Made In The USA To The Highest Quality Standards

    VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

    Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.

    Your pet's immune system is the key to its health! Here's why:

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

    Let’s face it. Your pet lives in a world filled with contamination.

    They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

    The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

    Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

    What do you do?

    You need to put your pet’s immune system in overdrive!

    Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

    The doctors agree

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”

    Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    Pet owners CAN make a difference.

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    – Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    More cats and dogs are being diagnosed with cancer than ever before. 

    “Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Frequently Asked Questions

    Verified Product Reviews

    average rating 4.7 out of 5
    Based on 1446 reviews
    • 5 Stars
      1199 Reviews
    • 4 Stars
      147 Reviews
    • 3 Stars
      68 Reviews
    • 2 Stars
      9 Reviews
    • 1 Star
      23 Reviews
    93% of reviewers would recommend this product to a friend
    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Customer photos and videos
    1446 Reviews
    Reviewed by Janine G.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5
    Pet Age
    1 - 3 Years
    Dog Breed
    Mixed Breed
    Cat Breed
    Mixed Breed
    Pet Problem(s)
    • Inflammation
    • Stress
    Will Consume Product
    Enjoyed
    Pet Happiness
    Tail Wagging

    It makes me know I’m doing the best for my pets.

    I got the Critical Immune Defense for my 17 year old cat. He’s doing better- back to jumping up on the bed! Now I have a year old puppy who seems to be liking it on her food. I figured this is a good way to start a healthy life for my newest pet.

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    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Thank you so much for sharing, Janine! Your 17-year-old cat is looking amazing—seeing him back to jumping on the bed is such a win! 😻 And your year-old puppy is absolutely adorable—what a great start to a healthy life for her. We love that you’re giving both your senior and your youngest the best care possible. Your dedication truly shines through! 💛

    Reviewed by Cecilia L.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    American Bulldog
    Pet Problem(s)
    • Tumor
    • Cancer

    Pet with lymphatic tumors

    I started using this product for my dog when I found out she have cancer I heard it’s a good product for critical situation like her I have faith this will help her

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    Pet Wellness Direct

    Thank you, Cecilia, for sharing your sweet girl’s story. We’re honored to be part of her journey and admire your strength and hope. 🐾. You’re doing such a great job helping her thrive 💛

    Reviewed by Melinda R.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5
    Pet Age
    10+ Years
    Cat Breed
    British Longhair
    Pet Problem(s)
    • Tumor
    • Low Energy
    Will Consume Product
    Enjoyed
    Pet Happiness
    Just Right

    Kittie is acting so much younger!

    My cat suki is about 11 years old and is a recent rescue. She has asthma and seasonal allergies. She also has chronic sinus draining which will require a scope to diagnose. It took quite some time to get her to eat her canned food with the Immune defense mixed in. Since she's been eating well and I can see changes in her energy! She's started having zoomies, often late at night!

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    Pet Wellness Direct

    Thank you, Melinda, for sharing sweet Suki’s story—her photos is precious! 😻 It’s amazing to hear that at 11, and with asthma, allergies, and sinus issues, she’s now full of energy and even getting the zoomies! You’re doing such a great job helping her thrive 💛

    Reviewed by Greg S.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Australian Shepherd
    Pet Problem(s)
    • Tumor
    • Joint Pain
    • Inflammation
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Make it a great day!

    My furry companion Niko has started the critical immune defense product in January. After a recent trip to vet to diagnose some issues, we became aware of this product and reading many reviews gave it a try. Well, his appetite has increased like none other he has had in years. We started out slow and then increased to the recommended dose at each meal. We are glad we tried the product and look forward to ordering some soon. Thank you much for this unique product. Best to all!

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    Pet Wellness Direct

    Hi Greg, Niko looks fantastic! 🐾💙 It’s wonderful to hear that since starting Critical Immune Defense in January, his appetite has improved like never before—what a great sign! You’ve done an amazing job introducing it slowly and finding what works best for him. We’re so happy you gave it a try and that it’s making a difference. Wishing you and Niko continued health and happiness—best to you both! 💕🐶

    Reviewed by Katherine D.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Pitbull Terrier
    Pet Problem(s)
    • Tumor
    Will Consume Product
    Enjoyed
    Pet Happiness
    Just Right

    The only supplement powder my dogs will eat

    My pit has a history of mast cell tumors. I’m hoping this will help ward off more developing. Both dogs love the flavor and expect it on their meals now.

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    Pet Wellness Direct

    Your Pit is beautiful! 🐾💙 I’m so glad both dogs love the flavor and now expect it on their meals—that’s a great sign! With your Pit’s history of mast cell tumors, you’re doing an incredible job being proactive. Wishing you both health and happiness! 💕🐶