Critical Immune Defense

Rated 4.7 out of 5
Based on 1064 reviews
Sale price$65.00 USD
Size: 1 Bottle
Free shipping on subscriptions & orders $75 or more.

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Your Pet's Immune System Is the Key to Its Health

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet. Let’s face it. Your dog and cat lives in a world filled with contamination. They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants. The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful.

    Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health. Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

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    50%

    Cancer Rates are skyrocketing

    More dogs and cats are being diagnosed with cancer than ever before.

    According to the Veterinary Cancer Society, almost 50% of all dogs and 32% of all cats over the age of 10 will develop cancer. Younger pets are also increasingly at risk.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    - Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    “One of the things that can be helpful is supporting your pet’s immune system with antioxidants to help its body to use its own natural defenses against disease. Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards. According to Dr. Edwards, another way to protect your pets is with all-natural health supplements.

    Pet Owners CAN Make A Difference

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins.”

    Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    “Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and mmunomodulatory properties that may help fight cancer and certain other diseases.”

    - Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    More dogs and cats are being diagnosed with cancer than ever before.

    According to the Veterinary Cancer Society, almost 50% of all dogs and 32% of all cats over the age of 10 will develop cancer. Younger pets are also increasingly at risk.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    - Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    “One of the things that can be helpful is supporting your pet’s immune system with antioxidants to help its body to use its own natural defenses against disease. Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards. According to Dr. Edwards, another way to protect your pets is with all-natural health supplements.

    Pet Owners CAN Make A Difference

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins.”

    Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    “Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and mmunomodulatory properties that may help fight cancer and certain other diseases.”

    - Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    The doctors agree

    Dr. Frank Markland

    Professor of Biochemistry and Molecular Medicine at the University of Southern California Keck School of Medicine.

    Dr. Shawn Messonnier

    Veterinary Medicine and author of "The Natural Vet's Guide to Preventing and Treating Cancer in Dogs"

    Dr. Jennifer Edwards

    Ponemah Veterinary Hospital

    Where you have seen us

    Critical Immune Defense

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    The all-natural solution. Trusted by veterinarians.

    Originally designed for veterinarians, VetSmart Formulas delivers the clinical-strength, quality and efficacy veterinarians demand of solutions they provide and recommend.

    Critical Immune Defense is 100% safe to use, has NO side effects, and can be used in conjunction with chemotherapy, steroid treatments and other medications.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Made In The USA To The Highest Quality Standards

    VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

    Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.

    Frequently Asked Questions

    Happy Customer Reviews

    average rating 4.7 out of 5
    Based on 1064 reviews
    • 5 Stars
      884 Reviews
    • 4 Stars
      107 Reviews
    • 3 Stars
      51 Reviews
    • 2 Stars
      7 Reviews
    • 1 Star
      15 Reviews
    93% of reviewers would recommend this product to a friend
    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Customer photos and videos
    1064 Reviews
    Reviewed by Marcy L.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    American Staffy
    Pet Problem(s)
    • Low Energy
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Great product

    My dog has so much more energy for a senior. We have another ultrasound to do and I am hoping it is good news like the last one was.

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    Effectiveness
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Thank you, Marcy, for sharing your experience with Critical Immune Defense! It's great to hear your senior American Staffy has more energy. 🌟🐾 The picture you shared is adorable—he looks so happy! Hoping for more good news from the upcoming ultrasound.

    Reviewed by Diana M.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Golden Retriever
    Pet Problem(s)
    • Joint Pain
    • Low Energy
    Will Consume Product
    Enjoyed
    Pet Happiness
    Tail Wagging

    New spunk!

    My 8 year old golden retriever has been experiencing some new sassiness since using Critical Immune Defense. He has more energy and is calmer at night. I recommend this product!

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Was this helpful?

    Pet Wellness Direct

    Hi Diana, Thank you for sharing your experience with Critical Immune Defense! It's heartwarming to hear that your 8-year-old Golden Retriever is more energetic and calmer at night. 🌟🐾 The picture you shared is adorable—he looks so happy! We're thrilled CID is making such a positive difference in his life!

    Reviewed by Butter D.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5
    Pet Age
    5 - 7 Years
    Dog Breed
    Pug
    Pet Problem(s)
    • Joint Pain
    • Inflammation
    • Cancer
    • Overweight
    Will Consume Product
    Enjoyed
    Pet Happiness
    Tail Wagging

    This is just my first canister. Pups seem to have a little more energy.

    My old pugs seem to have more energy. So I’m going to try another one. Butter did have cancer removed with two toes. And both dogs love the gravy when I had water.

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    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Was this helpful?

    Pet Wellness Direct

    Hi Butter, thank you for sharing your experience with Critical Immune Defense! It's wonderful to hear that your pugs enjoy the flavor and have more energy. 🌟🐾 His resilience after cancer surgery is truly inspiring. We're glad your pups are benefiting and look forward to more positive results!

    Reviewed by Georgia J.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Bullmastiff
    Pet Problem(s)
    • Cancer
    • Hip Pain
    • Limp
    Will Consume Product
    Devoured
    Pet Happiness
    Just Right

    For Nico

    Dog holding his own has been diagnosed with cancerous masses but he hasn't declined since I started him on this product

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    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Georgia, Thank you for sharing your experience with Critical Immune Defense. 🐾 His photo is handsome, and your dedication to his health is truly inspiring. Wishing you both continued health and happiness! 🐶💕

    Reviewed by Annie L.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Labrador
    Cat Breed
    Other
    Pet Problem(s)
    • Cancer
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Saving my dogs life

    I started giving my 12 year old Yellow Lab this amazing product after receiving a cancer diagnosis. He was given 9 months to live. I am so greatful in saying he passed that mark this passed April. He has kept up his energy level. He still acts like he is five. So since the great results I feed it to my whole pet family. I have three dogs and three cats. They are all doing great. I can't thank this company and this product enough.

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Thank you, Annie, for sharing your story. It's amazing to hear that Critical Immune Defense has helped him surpass his prognosis and keep his energy up! 🐾 His photos are adorable, and it's fantastic that your whole pet family is doing great. Your dedication to their health is inspiring! 🐶💕