Critical Immune Defense

Rated 4.7 out of 5
Based on 1182 reviews
Sale price$180.00 USD
Size: 3 Bottles
Free shipping on subscriptions AND all orders over $75

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Critical Immune Defense is a powder that you sprinkle just a small amount on your dog or cat's food. It TASTES GREAT - even for the most finicky of pets.

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    Made In The USA To The Highest Quality Standards

    VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

    Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.

    Your pet's immune system is the key to its health! Here's why:

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

    Let’s face it. Your pet lives in a world filled with contamination.

    They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

    The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

    Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

    What do you do?

    You need to put your pet’s immune system in overdrive!

    Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

    The doctors agree

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”

    Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    Pet owners CAN make a difference.

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    – Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    More cats and dogs are being diagnosed with cancer than ever before. 

    “Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Frequently Asked Questions

    Verified Product Reviews

    average rating 4.7 out of 5
    Based on 1182 reviews
    • 5 Stars
      979 Reviews
    • 4 Stars
      117 Reviews
    • 3 Stars
      58 Reviews
    • 2 Stars
      7 Reviews
    • 1 Star
      21 Reviews
    93% of reviewers would recommend this product to a friend
    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Customer photos and videos
    1182 Reviews
    Reviewed by Betsey V.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5
    Pet Age
    7 - 10 Years
    Dog Breed
    Labrador
    Pet Problem(s)
    • Tumor
    Will Consume Product
    Enjoyed
    Pet Happiness
    Just Right

    My dog loves this stuff!

    I am on the 4th jar. Not sure of progress. Lumps seem the same. Should I continue?

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    Effectiveness
    Rated 0 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Betsey, thank you so much for sharing your experience! 🐾 It’s wonderful to hear that your Labrador loves Critical Immune Defense, and I can see why you’re hoping to see more progress with the lumps. Sometimes it can take a bit longer for visible changes. Mitchell looks great in his picture, and we're rooting for his continued health! 💙

    Reviewed by Leesa F.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Golden Retriever
    Pet Problem(s)
    • Hip Pain
    • Stress
    • Bad Breath
    • Overweight
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Working wonderfully on my 2 older dogs

    I have a 12.5 yr old Golden Retriever/ Husky mix who had some skin problems and has had x2 TPlo surgeries… this has done wonders for him. Also our 10.5 Golden Retriever is a nervous Nelly, and would get so distressed if we boarded them she would end up with pancreatitis. Since they have been on this for over a year, we only ent to vet this yr for rabies vax and that was it. It’s expensive but worth every penny.

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
    Was this helpful?

    Pet Wellness Direct

    Thank you Leesa so much for sharing! 🐾 It’s amazing to hear how much your 12.5-year-old Golden Retriever/Husky mix has improved after TPLO surgeries and skin issues, and your 10.5-year-old Golden Retriever looks so happy and healthy too! 💙 The fact that you’ve only needed a vet visit for rabies this year is fantastic. Your care is really making a difference!

    Reviewed by Sylvia J.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    10+ Years
    Dog Breed
    Labrador
    Pet Problem(s)
    • Tumor
    • Cancer
    • Overweight
    • Hip Pain
    • Limp
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    Mitchell’s journey

    Critically immune really help. He has more energy, he doesn’t limp anymore

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Sylvia, thank you for sharing! 🐾 It’s wonderful to hear that Critical Immune Defense has boosted his energy and stopped the limping. He looks so adorable in his photo! Wishing you both continued health and happiness! ❤️

    Reviewed by Liz D.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    7 - 10 Years
    Cat Breed
    American Shorthair
    Pet Problem(s)
    • Tumor
    • Cancer
    • Bad Breath
    • Stress
    Will Consume Product
    Nibbled
    Pet Happiness
    Just Right

    Sami-My loving rescue cat

    I do rescue work and care for 14 cats currently…

    Sami was a beautiful sweet cat who was part of my colony of cats I fed for 8 yrs.

    She developed an aggressive sarcoma in her leg last yr.

    I couldn’t give up on her so I had her leg removed and brought her in my home in a playpen. Her oncologist told me if she survived a year she could beat the disease.

    I gave her the critical immune powder every morning and I believe it truly helped her until 10 months later when she stopped eating.

    Unfortunately, the cancer had returned and she passed away last may…

    But I truly believe I would not have had her as long as I did if I hadn’t given her ur product.

    And I give it to several other cats as well and have seen improvement in health and coats!

    So thank you!!

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    Effectiveness
    Rated 2 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Liz, thank you, or sharing Sami's touching story. It’s clear how much love and care you gave her and we're glad Critical Immune Defense helped give you those extra months together. Sami was a beautiful cat, and she was lucky to have you. 🐾💙

    Reviewed by Tera
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5
    Pet Age
    5 - 7 Years
    Dog Breed
    Doberman Pinscher
    Pet Problem(s)
    • Limp
    • Hip Pain
    • Joint Pain
    • Inflammation
    Will Consume Product
    Devoured
    Pet Happiness
    Tail Wagging

    1 month down many more to go

    So far it seems to work great, we are expecting our second bottle any day. They both love the taste, our mix kye has arthritis and was limping she seems to be more energetic and not in so much pain. Our doberman has not been itching. We All Love ot so far . I have sprinkled it on the cat's food and they like it too.

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    Effectiveness
    Rated 1 on a scale of minus 2 to 2, where minus 2 is Low, 0 is Medium and 2 is High
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    Pet Wellness Direct

    Hi Tera, Thank you for sharing! 💛 It’s great to hear Kye is more energetic and in less pain, and your Doberman is itch-free! Even the cats are loving it! They all look so happy in their picture. Here’s to many more healthy months ahead! 🐾