Critical Immune Defense

Sale price$65.00 USD
Size: Small Bottle | 70 Scoops

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Critical Immune Defense is a powder that you sprinkle just a small amount on your dog or cat's food. It TASTES GREAT - even for the most finicky of pets.

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    Your pet's immune system is the key to its health! Here's why:

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

    Let’s face it. Your pet lives in a world filled with contamination.

    They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

    The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

    Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

    What do you do?

    You need to put your pet’s immune system in overdrive!

    Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

    The doctors agree

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”

    Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    Pet owners CAN make a difference.

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    – Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    More cats and dogs are being diagnosed with cancer than ever before. 

    “Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Frequently Asked Questions

    Verified Product Reviews

    average rating 4.7 out of 5
    Based on 1601 reviews
    • 5 Stars
      1322 Reviews
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      164 Reviews
    • 3 Stars
      81 Reviews
    • 2 Stars
      10 Reviews
    • 1 Star
      24 Reviews
    93% of reviewers would recommend this product to a friend
    Customer photos and videos
    1601 Reviews
    Reviewed by Julia B.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    Great product!

    My cat had cancer around three years ago. I started her on Critical Immune Defense and she’s still with us at almost 16.

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    Pet Wellness Direct

    Hi Julia, That’s amazing to hear! 💕 We’re so glad your sweet cat is still thriving at almost 16 after her cancer diagnosis—what a wonderful testament to her strength 🌟. She’s clearly so loved and cared for!

    Reviewed by Leslie P.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5

    My dog loves it!!

    So far my dog loves the taste of this powder and I add it daily to his food. He’s a thirteen year old rescue dog I’ve had since he was eight and he’s had a lot of allergies as well as gut issues and extreme anxiety! He was on a lot of medication and had liver problems a year ago this spring, and I had to remove some of his meds since it was causing liver damage. He was at risk of dying if we didn’t change his protocol so I stopped giving him all kibble and I began making his food myself. I serve him daily with ground meat and veggies. I’m now also adding in Immune Defense. I am hoping and praying that this helps my dog stop his incessant itching as well as his anxiety. He’s only been on it three weeks so it’s probably too soon to tell but he does enjoy the flavor and I feel hopeful it’ll help his gut issues which is the key to his poor health. He seems more energetic and I’m definitely thankful for finding this product. I’ll update my review in a few months to see where we’re at!!

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    Pet Wellness Direct

    Hi Leslie, thank you for sharing your story! 💚 Your 13-year-old rescue sounds like such a strong and resilient boy, and it’s wonderful to hear he loves the taste of Critical Immune Defense. We’re so glad you’ve found a routine that works for him with home-cooked meals, and it’s heartwarming to know he already seems more energetic. 🌟 Hoping the itching and anxiety continue to ease with time—you’re giving him such amazing care and he’s lucky to have you by his side!

    Reviewed by Debbie B.
    Verified Buyer
    Review posted
    Rated 3 out of 5

    No change

    We have been giving this to our 16yo doodle for lipoma. We have not seen a change in the lump but it also has not grown nor has she gotten any more. Some days are better than others but it’s worth a try. Every dog is different. Love them while you have them!

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    Pet Wellness Direct

    Hi Debbie, thank you for sharing about your sweet 16-year-old doodle. 💕 Even though the lump hasn’t changed, it’s great news it hasn’t grown or spread. 🌟

    Reviewed by Deborah H.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    I believe it's working

    My 18 month golden retriever was recently diagnosed with oral cancer. He also had a mass on his side which was on his first CT scan. I ordered CID and within 2 1/2 weeks it was gone and did not show up on his follow-up CT scan a month later. I am going to continue giving him this in hopes that it will stop the cancer from returning. He had 5 radiation treatments two weeks ago and will start chemo pills in the next few days. I have recommended this to a few people I know also dealing with cancer in their dogs.

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    Pet Wellness Direct

    Hi Deborah, thank you for sharing your pup's journey.💚 It’s amazing that the mass disappeared on his follow-up CT scan after starting Critical Immune Defense, and we’re so glad he’s feeling supported through treatments. His photo is heart-melting 🌟—he’s such a strong, beautiful pup, and we’ll be cheering you both on every step of the way.

    Reviewed by SUZANNE M.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    I highly suggest the Vets smart critical immune defense for dogs

    My German shepherd was not quite 10 years old and was not doing very well so I decided to put her on the Vetsmart auto immune defense because her littermate sister had just died of a blood cancer and when we went to see the oncologist she suggested giving the dogs mushrooms for their immune system and health. She is now coming up 12 years old in December and has never done better since she was a puppy and I highly suggest this to my friends and family and all dog owners

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    Pet Wellness Direct

    Hi Suzanne, thank you for sharing your story and review. 💚 We’re so sorry to hear about her sister, but it’s inspiring to know that after starting Critical Immune Defense, your girl has gone from struggling at 10 to thriving as she approaches 12. Her photos are absolutely beautiful—we’re honored to be part of her journey and grateful you’re recommending us to others who love their dogs as much as you do!