Critical Immune Defense

Sale price$65.00 USD
Size: Small Bottle | 70 Scoops

Protect Your Pet from Life-Threatening Disease. A safe, all-natural immune booster that can add years to the life of your pet. Made in the USA.

✔︎  Boosts immune system
✔︎  Reduces inflammation
✔︎  Promotes normal cell growth
✔︎  Protects against toxins in food, water & environment
✔︎  Supports long-term health in dogs and cats

    Strengthens the Immune System

    Boosts the growth of "good" cells that fight disease and are essential for your pet’s long-term health.

    Promotes Normal Cell Growth

    Improves the immune system’s ability to monitor cell development and eliminate abnormalities.

    Can Extend Your Pet's Life

    Includes powerful antioxidants that reduce cellular aging and promote greater health & longevity.

    Protects Against Diseases

    Eliminates harmful pathogens such as bacteria and viruses that cause inflammation and infection.

    Works With Prescription Medications

    Great for pets on chemotherapy treatment, prescription steroids, pain medication & more.

    Backed By Science

    Asian cultures have used these all-natural ingredients to treat diseases and cancers for 1,000's of years.

    Critical Immune Defense is a powder that you sprinkle just a small amount on your dog or cat's food. It TASTES GREAT - even for the most finicky of pets.

    Key Ingredients

    Turkey Tail Mushroom

    This colorful mushroom has been used for centuries in Asia to treat disease and contains high levels of active compounds that have been proven to inhibit the growth of cancerous tumors.

    Reishi Mushroom

    This woody fungi is known as one of the top natural superfoods and has been used for 1000s of years to fight inflammation, cancer, heart disease, hormonal imbalances and more.

    Shiitake Mushroom

    According to the Journal of Nutrition, shiitake mushrooms provide antiviral, antibacterial and antifungal protection and help to control blood sugar and reduce inflammation.

    Maitake Mushroom

    Maitake mushrooms are loaded with vitamins and active ingredients that stimulate the immune system and promote natural hormone balance and healthy cell growth.

    White Turmeric Root Extract

    Turmeric has been used for centuries to reduce pain and inflammation. Its active ingredient, curcumin, has proven to be effective at blocking the growth of certain cancers and protecting against neurodegenerative diseases, arthritis, cardiovascular risks and
    liver damage.

    Ingredients & Usage Direction:

    (Approximately 70 Scoops Per Container)

    (Approximately 70 Scoops Per Container)

    Made In The USA To The Highest Quality Standards

    VetSmart Formulas is made in the USA in FDA audited facilities which adhere to cGMP and are audited by Underwriter Labs.

    Every ingredient is carefully inspected and tested before processing, ensuring a consistently safe, high-quality product for your beloved dog’s health.

    Your pet's immune system is the key to its health! Here's why:

    In today’s world, viruses and diseases are rampant, and it can be challenging to protect your pet.

    Let’s face it. Your pet lives in a world filled with contamination.

    They spend 90% of their waking hours on the floor, mopping up toxins, chemicals, and pollutants.

    The household cleaning products, fertilizer on the lawn, and preservatives in their foods can be harmful. Bacteria, airborne contaminants, and viruses transmitted by humans can challenge their health.

    Most pets do not eat an optimal diet, and likely do not get as much exercise as they require.

    What do you do?

    You need to put your pet’s immune system in overdrive!

    Research shows that a well-balanced and functional immune system is essential to your pet’s overall health and well-being.

    The doctors agree

    Mushrooms = Anticancer Activity

    “As a pet lover, I think it makes sense that the compounds in mushrooms be included in your pet’s diet or included by nutritional supplements. Certain mushrooms contain agents with anticancer activity and immunomodulatory properties that may help fight cancer and certain other diseases.”

    Dr. Frank Markland, Professor of biochemistry and molecular medicine at the University of Southern California Keck School of Medicine.

    Pet owners CAN make a difference.

    “It is the responsibility of the pet owner to do everything possible to minimize the risk of cancer in their pets. This includes a sensible lifestyle with sufficient exercise, weight management, drinking clean water, healthy food intake, and avoiding toxins. Giving your pets a high-quality antioxidant supplement is highly recommended to further reduce the risk of cancer.”

    – Dr. Shawn Messonnier, Veterinarian and Founder of Paws & Claws Animal Hospital in Plano, Texas.

    More cats and dogs are being diagnosed with cancer than ever before. 

    “Certain mushrooms and turmeric may be beneficial in helping your pet to boost its immune system to fight diseases,” explains Edwards.

    “Cancer is affecting our pets at alarming rates, and it is devastating for both the families of these pets as well as the pets themselves. I am seeing this in my practice on a regular basis.”

    Dr. Jennifer Edwards, Veterinarian at Ponemah Veterinary Hospital in Amherst, New Hampshire.

    No Artificial Colors

    No Artificial Flavors

    Wheat-free

    Frequently Asked Questions

    Verified Product Reviews

    average rating 4.7 out of 5
    Based on 1589 reviews
    • 5 Stars
      1312 Reviews
    • 4 Stars
      163 Reviews
    • 3 Stars
      80 Reviews
    • 2 Stars
      10 Reviews
    • 1 Star
      24 Reviews
    93% of reviewers would recommend this product to a friend
    1589 Reviews
    Reviewed by Clarence S.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    Mast Cell cancer gone!

    My dog was diagnosed with an aggressive Mast Cell cancer nearly 4 years ago. With chemo, his prognosis was 12 months to live. Without treatment, 4 months. We contacted Fido-cure for advanced chemo to complement our oncologists' protocols, deployed Benadryl 2x daily, accompanied by Tagamet 2x daily to block both histamine pathways and we bought this mushroom product for immediate use. Our dog is ALIVE and cancer-free. What worked? Who knows but the odds of him being alive today are less than 10%.

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    Pet Wellness Direct

    Hi Clarence, thank you so much for sharing your dog’s incredible story!🐾 To hear that after being diagnosed with aggressive Mast Cell cancer nearly 4 years ago—and given such a short prognosis—he is still alive and now cancer-free is truly inspiring. It’s wonderful that with the support of your oncologist, advanced treatments, and Critical Immune Defense, he’s beaten the odds and is thriving today. His photos show such a strong and resilient spirit 💛, and we’re honored to have played a role in his amazing journey.

    Reviewed by Wendy N.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    I think it makes a difference

    I have 4 large dogs so they are not getting the full recommended dose but they get a scoop once a day and I am seeing a little difference in my 2 older (8 yr old) girls

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    Pet Wellness Direct

    Hi Wendy, thank you for sharing your experience with your four pups! 🐾 It’s wonderful to hear that even with a smaller scoop each day, you’re already noticing a difference in your two 8-year-old girls. That extra boost of energy and wellness at their age is so encouraging. We’re thrilled to be a part of keeping them healthy and active alongside the rest of your pack!

    Reviewed by Kathleen H.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 4 out of 5

    Help for Spice?

    I was told at Spice's last check up he has the start of kidney disease. I read so many reviews that it has help so many other pet so I feel I only have time to gain with Spice by trying your product. He goes for more blood work in a month and at that time I hope to see improvement. He seems to have more spry moments so fingers are crossed.

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    Pet Wellness Direct

    Thank you for sharing Spice’s update. 🐾 We’re glad to hear he’s having more spry moments since starting Critical Immune Defense, and we’ll be hoping for good news at his upcoming blood work. His photo shows such a sweet boy 💛, and we’re honored to be part of his care journey.

    Reviewed by Christine M.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    Excellent!

    I originally bought this for my cat for sneezing, wheezing. However he kept turning away from it. However my 30lb terrier mix rescue from Mississipi had terrible allergic reactions to the New England seasonal changes. She would shake her head, scratch at her ears , show signs of distress. I consulted my vet who didn't seem concerned , offered no prescription or suggestion. I did a deep dive on the internet and came across Critical Immune Defense. Our pup has been on this formula for over a year , with 100% improvement toward her allergies. I trust the ingredients in this formula as something I would take myself. So many great benefits supplementing with mushrooms. Customer service is great as well. I highly recommend this product.

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    Pet Wellness Direct

    Hi Christine, thank you for sharing your experience! 🐾 We’re so happy to hear your rescue pup is finally free from her seasonal allergy struggles after a year on Critical Immune Defense. It’s wonderful she’s comfortable and happy again, and her photo shows such a bright, resilient pup 💛. We’re honored to be part of her wellness journey and truly appreciate your kind words about our customer service!

    Reviewed by Steven C.
    Verified Buyer
    Review posted
    I recommend this product
    Rated 5 out of 5

    Has helped our Cat's nasal condition

    We have a 7 yo British Shorthair who we unknowingly got from a not very reputable breeder,

    She started with nasal discharge the day we brought her home, she then at 2yo almost died from FIP, thankfully we found the proper anti-viral medication through the FIP Warriors that saver her life. While on the anti viral treatment, her nasal issue went away. once cured and off the meds, her nasal discharge returned, we have tried everything, lysine, Famciclovir and other natural remedies. Pet Wellness Critical Immune Defense is the only product that has shown any improvement. While not perfect, her nasal issues have decreased enough that she is back to a happy, playful cat.

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    Pet Wellness Direct

    Hi Steven, thank you for sharing your British Shorthair’s story! 🐾 After all she’s been through with FIP and ongoing nasal issues, it’s wonderful to hear that Critical Immune Defense has helped ease her symptoms so she can enjoy life as a happy, playful 7-year-old. Her photo and video shows such a beautiful, resilient girl 💛, and we’re so glad she’s thriving with your care.